Found 21 matching trials
Aumolertinib With Chemotherapy or Alone Compared With Osimertinib in Patients With Epidermal Growth Factor Receptor-Mutant Non-Small Cell Lung Cancer PHASE3 Aumolertinib is a third-generation epidermal growth factor receptor (EGFR) ...
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Highlands Oncology Group
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A Phase III Study to Assess the Efficacy and Safety of Almonertinib Versus Platinum-based Chemotherapy as First-line Therapy in Patients With Locally Advanced or Metastatic NSCLC Harbouring Uncommon EGFR Mutation PHASE3 To assess the efficacy and safety of Almonertinib versus platinum-based che...
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Sun yat-sen Univerisity Cancer Center
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Aumolertinib in EGFR-Mutant Resected Stage IB-IIIA NSCLC (AERESA). PHASE2 Aumolertinib (almonertinib; HS-10296) is a novel third-generation EGFR-TKI ...
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Sun Yat-sen University Cancer Center
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Almonertinib as First-line Treatment in Patients With EGFR Mutations Positive in Advanced NSCLC With Brain Metastases PHASE2 This is a prospective, open-label, multi-center, single-arm clinical trial...
Location
Cancer Hospital Affiliated to University of Chinese Academy of Sciences
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A Phase III Study to Assess the Effects of Almonertinib Following Chemoradiation in Patients With Stage III Unresectable Non-small Cell Lung Cancer PHASE3 To assess the efficacy and safety of Almonertinib versus placebo following ...
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Shandong Cancer Hospital
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PLATFORM Study of Precision Medicine for Rare Tumors PHASE2 A Phase II, open label, non-randomized, multiple-arm, single-center clinica...
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Cancer hospital Chinese Academy of Medical Sciences
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Aumolertinib with or Without Chemotherapy As 1st Line Treatment in Locally Advanced or Metastatic Non-Small Cell Lung Cancer with Sensitizing EGFR Mutations PHASE3 To assess the efficacy and safety of Aumolertinib plus chemotherapy versus ...
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Active Not Recruiting
Location
Shanghai Chest Hospital
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Neoadjuvant HS-10296 (Almonertinib) Therapy for Potential Resectable Stage III EGFR Mutation-Positive Non-small Cell Lung Cancer PHASE2 This is a phase II, single-arm, open-label study to evaluate the efficacy a...
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Active Not Recruiting
Location
Shanghai Pulmonary Hospital
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A Study of HS-20117 Combined With Aumolertinib in Participants With Advanced Non-Squamous Non-Small Cell Lung Cancer PHASE2 HS-20117 is a fully-human EGFR-MET immunoglobulin G1(IgG1)-like bispecific ...
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Tianjin Medical University Cancer Institute and Hospital
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An Open-Label, Single-Dose, Parallel-Group Study of the Pharmacokinetics and Safety of EQ143 PHASE1 Participants aged 18 to 75 years with severe hepatic impairment (Child-Pugh...
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American Institute Research
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